Analysis Methods Supplement for: Classification and Diagnostic Prediction of Cancers using Gene Expression Profiling and Artificial Neural Networks

نویسندگان

  • Javed Khan
  • Jun S. Wei
  • Markus Ringnér
  • Lao H. Saal
  • Marc Ladanyi
  • Frank Westermann
  • Frank Berthold
  • Manfred Schwab
  • Cristina R. Antonescu
  • Carsten Peterson
  • Paul S. Meltzer
چکیده

In total, expression levels from 6567 genes are measured for each of the 88 samples, where 63 are labeled calibration samples and 25 represent blind tests. In the analysis we used the red intensity (ri) and the relative red intensity (rri). Genes are omitted if for any of the samples ri is less than 20. With this cut we are left with 2308 genes, which are used below for the analysis. The cut in ri mainly removes spots for which the image analysis failed. In Fig. 1 the number of genes each sample removes is shown. We used the natural logarithm of rri as a measure of the expression levels.

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تاریخ انتشار 2001